Structure of PDB 3toz Chain A

Receptor sequence
>3tozA (length=291) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence]
MTNKITERITGHTELIGLIATPIRHSLSPTMHNEAFAKLGLDYVYLAFEV
GDKELKDVVQGFRAMNLRGWNVSMPNKTNIHKYLDKLSPAAELVGAVNTV
VNDDGVLTGHITDGTGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAA
LDGVKEISIFNRKDDFYANAEKTVEKINSKTDCKAQLFDIEDHEQLRKEI
AESVIFTNATGVGMKPFEGETLLPSADMLRPELIVSDVVYKPTKTRLLEI
AEEQGCQTLNGLGMMLWQGAKAFEIWTHKEMPVDYIKEILF
3D structure
PDB3toz 2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.25: shikimate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G137 A138 G139 G140 A141 N161 R162 D164 F166 T210 G211 V212 M214 F217 V238 Y240 G261 M264 M265 G137 A138 G139 G140 A141 N161 R162 D164 F166 T210 G211 V212 M214 F217 V238 Y240 G261 M264 M265
Gene Ontology
Molecular Function
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3toz, PDBe:3toz, PDBj:3toz
PDBsum3toz
PubMed
UniProtQ8Y9N5|AROE_LISMO Shikimate dehydrogenase (NADP(+)) (Gene Name=aroE)

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