Structure of PDB 3tn7 Chain A

Receptor sequence
>3tn7A (length=234) Species: 604354 (Thermococcus sibiricus MM 739) [Search protein sequence]
MKVAVITGASRGIGEAIARALARDGYALALGARSVDRLEKIAHELMQEQG
VEVFYHHLDVSKAESVEEFSKKVLERFGDVDVVVANAGLGYFKRLEELSE
EEFHEMIEVNLLGVWRTLKAFLDSLKRTGGLALVTTSDVSARLIPYGGGY
VSTKWAARALVRTFQIENPDVRFFELRPGAVDTYFGGSKPGKPKEKGYLK
PDEIAEAVRCLLKLPKDVRVEELMLRSVYQRPEY
3D structure
PDB3tn7 Structural insight into the molecular basis of polyextremophilicity of short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Thermococcus sibiricus.
ChainA
Resolution1.68 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D138 Y150 K154 P193
Catalytic site (residue number reindexed from 1) D138 Y150 K154 P193
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NJP A G8 S10 R11 G12 I13 R33 S34 L58 D59 V60 N86 A87 G88 T135 T136 S137 Y150 K154 P178 G179 A180 V181 T183 Y184 F185 G8 S10 R11 G12 I13 R33 S34 L58 D59 V60 N86 A87 G88 T135 T136 S137 Y150 K154 P178 G179 A180 V181 T183 Y184 F185
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3tn7, PDBe:3tn7, PDBj:3tn7
PDBsum3tn7
PubMed22885278
UniProtC6A190

[Back to BioLiP]