Structure of PDB 3tka Chain A

Receptor sequence
>3tkaA (length=283) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
TTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRD
PQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSP
QLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGE
ERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKHPATRTFQAVRIW
VNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGRQ
LRALGKLMPGEEEVAENPRARSSVLRIAERTNA
3D structure
PDB3tka Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.199: 16S rRNA (cytosine(1402)-N(4))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A T31 F32 G33 R34 G36 H37 D55 R56 P78 F79 D101 G103 V104 S105 M128 E218 T24 F25 G26 R27 G29 H30 D48 R49 P71 F72 D94 G96 V97 S98 M121 E207
BS02 CTN A D147 W211 D140 W200
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0042803 protein homodimerization activity
GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3tka, PDBe:3tka, PDBj:3tka
PDBsum3tka
PubMed22561317
UniProtP60390|RSMH_ECOLI Ribosomal RNA small subunit methyltransferase H (Gene Name=rsmH)

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