Structure of PDB 3tj6 Chain A

Receptor sequence
>3tj6A (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
MPVFHTRTIESILEPVAQQISHLVIMHEEGKAIPDLTAPVAAVQAAVSNL
VRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPA
RDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETM
EDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPV
LISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWD
EDA
3D structure
PDB3tj6 The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
ChainA
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I12 Q19 H22 L23 M26 V47 A50 L54 V57 I115 L123 F126 D127 I12 Q19 H22 L23 M26 V43 A46 L50 V53 I111 L119 F122 D123
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tj6, PDBe:3tj6, PDBj:3tj6
PDBsum3tj6
PubMed21841197
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

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