Structure of PDB 3tiw Chain A

Receptor sequence
>3tiwA (length=160) Species: 9606 (Homo sapiens) [Search protein sequence]
RPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIV
LSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDD
TGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIV
APDTVIHCEG
3D structure
PDB3tiw The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
ChainA
Resolution1.802 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.6: vesicle-fusing ATPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D35 F52 R53 G54 I70 V108 Y110 A142 Y143 R144 I175 D14 F31 R32 G33 I49 V87 Y89 A116 Y117 R118 I149
External links
PDB RCSB:3tiw, PDBe:3tiw, PDBj:3tiw
PDBsum3tiw
PubMed21914798
UniProtP55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase (Gene Name=VCP)

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