Structure of PDB 3tin Chain A

Receptor sequence
>3tinA (length=312) Species: 8364 (Xenopus tropicalis) [Search protein sequence]
GSFTYTFVVRDENSTVYAEVAKILLASGQWKRLKRDNPKFNLMLGERNRL
PFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELTETCTWFPES
YVIYPEREEFRSSFNKKKENEEGNVWIAKSSSGGILISSDATELLDFIDN
QGQVHVIQKYLESPLLLEPGHRKFDIRSWVLVDNQYNIYLYREGVLRTSS
EGNEMFFEEFNQYLVTSLNINLENSILCQIKEIIRVCLSCLEPAISTKYL
PYHSFQLFGFDFMVDKNLKVWLIEVNGAPACAQKLYAELCKGIVDLAISS
VFPLNENVFIKL
3D structure
PDB3tin Tubulin tyrosine ligase structure reveals adaptation of an ancient fold to bind and modify tubulin.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.25: tubulin--tyrosine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A K150 Y185 L186 D200 M320 K129 Y160 L161 D175 M263
BS02 MG A Y14 N63 Y17 N66
BS03 MG A Y65 R66 Y309 S311 Y68 R69 Y252 S254
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0036211 protein modification process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3tin, PDBe:3tin, PDBj:3tin
PDBsum3tin
PubMed22020298
UniProtF6Z895

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