Structure of PDB 3tho Chain A

Receptor sequence
>3thoA (length=357) Species: 2336 (Thermotoga maritima) [Search protein sequence]
GHMRPERLTVRNFLGLKNVDIEFQSGITVVEGPNGAGKSSLFEAISFALF
GNGIRYPNSYDYVNRNAVDGTARLVFQFERGGKRYEIIREINALQRKHNA
KLSEILENGKKAAIAAKPTSVKQEVEKILGIEHRTFIRTVFLPQGEIDKL
LISPPSEITEIISDVFQSKETLEKLEKLLKEKMKKLENEISSSLEKKLKE
MSDEYNNLDLLRKYLFDKSNFSRYFTGRVLEAVLKRTKAYLDILTNGRFD
IDFDDEKGGFIIKDWGIERPARGLSGGERALISISLAMSLAEVASGRLDA
FFIDEGFSSLCTENKEKIASVLKELERLNKVIVFITCDREFSEAFDRKLR
ITGGVVV
3D structure
PDB3tho ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex.
ChainA
Resolution2.6081 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A L12 G13 N32 G33 A34 G35 K36 S37 S38 R53 Y54 V61 N62 R63 E798 L14 G15 N34 G35 A36 G37 K38 S39 S40 R55 Y56 V63 N64 R65 E305
BS02 MG A S37 E798 S39 E305
Gene Ontology
Molecular Function
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006302 double-strand break repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3tho, PDBe:3tho, PDBj:3tho
PDBsum3tho
PubMed21937514
UniProtQ9X1X1|RAD50_THEMA DNA double-strand break repair Rad50 ATPase (Gene Name=rad50)

[Back to BioLiP]