Structure of PDB 3thn Chain A

Receptor sequence
>3thnA (length=313) Species: 2336 (Thermotoga maritima) [Search protein sequence]
MKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLT
GDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNQDWKGLKLFGNFV
TSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFF
LESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGREIIINRALIPSVVD
YAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPP
RYERIDASPLPLKTLYYKKIDTSALKSIRDSCRNFPGYVRVVYEEDSLPD
LMGEIDNLVKIER
3D structure
PDB3thn ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex.
ChainA
Resolution2.811 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D14 H16 D58 H216 H218 D8 H10 D52 H206 H208
BS02 MN A D58 N93 H180 H216 D52 N87 H174 H206
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
Biological Process
GO:0006259 DNA metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3thn, PDBe:3thn, PDBj:3thn
PDBsum3thn
PubMed21937514
UniProtQ9X1X0|MRE11_THEMA DNA double-strand break repair protein Mre11 (Gene Name=mre11)

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