Structure of PDB 3th0 Chain A

Receptor sequence
>3th0A (length=552) Species: 10754 (Lederbergvirus P22) [Search protein sequence]
YSIEADKKFKYSVKLSDYPTLQDAASAAVDGLLIDRDYNFYGGETVDFGG
KVLTIECKAKFIGDGNLIFTKLGKGSRIAGVFMESTTTPWVIKPWTDDNQ
WLTDAAAVVATLKQSKTDGYQPTVSDYVKFPGIETLLPPNAKGQNITSTL
EIRECIGVEVHRASGLMAGFLFRGCHFCKMVDANNPSGGKDGIITFENLS
GDWGKGNYVIGGRTSYGSVSSAQFLRNNGGFERDGGVIGFTSYRAGESGV
KTWQGTVGSTTSRNYNLQFRDSVVIYPVWDGFDLGADTDMNPELDRPGDY
PITQYPLHQLPLNHLIDNLLVRGALGVGFGMDGKGMYVSNITVEDCAGSG
AYLLTHESVFTNIAIIDTNTKDFQANQIYISGACRVNGLRLIGIRSGQSL
TIDAPNSTVSGITGMVDPSRINVANLAEEGLGNIRANSFGYDSAAIKLRI
HKLSKTLDSGALYSHINGGAGSGSAYTQLTAISGSTPDAVSLKVNHKDCR
GAEIPFVPDIASDDFIKDSSCFLPYWENNSTSLKALVKKPNGELVRLTLA
TL
3D structure
PDB3th0 An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RAM A S237 E359 K363 Q366 W391 D395 S125 E247 K251 Q254 W279 D283 PDBbind-CN: -logKd/Ki=4.12,Kd=75.8uM
BS02 MAN A K363 Q366 K251 Q254 PDBbind-CN: -logKd/Ki=4.12,Kd=75.8uM
BS03 GLA A E359 W365 E247 W253 PDBbind-CN: -logKd/Ki=4.12,Kd=75.8uM
External links
PDB RCSB:3th0, PDBe:3th0, PDBj:3th0
PDBsum3th0
PubMed23292517
UniProtP12528|FIBER_BPP22 Tail spike protein (Gene Name=9)

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