Structure of PDB 3tg6 Chain A

Receptor sequence
>3tg6A (length=430) Species: 381518 (Influenza A virus (A/Wilson-Smith/1933(H1N1))) [Search protein sequence]
ATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAF
KTGGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWH
SNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMV
MELIRMIKGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAEF
EDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDP
FRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTKVV
PRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASS
GQISIQPTFSVQRNLPFDRPTIMAAFDMRTEIIRLMESARPEDVSFQGRG
VFELSDEKATSPIVPSFGSYFFGDNAEEYD
3D structure
PDB3tg6 Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0MM A Y289 D302 R305 L306 N309 Y236 D249 R252 L253 N256
BS02 0MM A Y52 E53 R99 W104 Y313 S376 Y31 E32 R59 W64 Y260 S323
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tg6, PDBe:3tg6, PDBj:3tg6
PDBsum3tg6
PubMed
UniProtQ1K9H2

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