Structure of PDB 3tg2 Chain A

Receptor sequence
>3tg2A (length=205) Species: 666 (Vibrio cholerae) [Search protein sequence]
AIPKIASYPLPVSLPTNKVDWRIDASRAVLLIHNMQEYFVHYFDSQAEPI
PSLIKHIQQLKAHAKQAGIPVVYTAQPANQDPAERALLSDFWGPGLSEET
AIIAPLAPESGDVQLTKWRYSAFKKSPLLDWLRETGRDQLIITGVYAHIG
ILSTALDAFMFDIQPFVIGDGVADFSLSDHEFSLRYISGRTGAVKSTQQA
CLEIA
3D structure
PDB3tg2 Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction
ChainA
Resolution1.101 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H34 N35 K118
Catalytic site (residue number reindexed from 1) H33 N34 K117
Enzyme Commision number 3.3.2.1: isochorismatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ISC A I3 H34 N35 F40 Q77 R86 W93 Y121 V146 Y147 I150 G151 I2 H33 N34 F39 Q76 R85 W92 Y120 V145 Y146 I149 G150
Gene Ontology
Molecular Function
GO:0008908 isochorismatase activity

View graph for
Molecular Function
External links
PDB RCSB:3tg2, PDBe:3tg2, PDBj:3tg2
PDBsum3tg2
PubMed22993087
UniProtP0C6D3|VIBB_VIBCH Vibriobactin-specific isochorismatase (Gene Name=vibB)

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