Structure of PDB 3tez Chain A

Receptor sequence
>3tezA (length=700) Species: 1392 (Bacillus anthracis) [Search protein sequence]
SSQGLLGYYFSDLNFQAPMVVTSSTTGDLSIPSSELENIPSENQYFQSAI
WSGFIKVKKSDEYTFATSADNHVTMWVDDQEVINKASNSNKIRLEKGRLY
QIKIQYQRENPTEKGLDFKLYWTDSQNKKEVISSDNLQLPELKQKSSNSR
KKRSTSAGPTVPDRDNDGIPDSLEVEGYTVDVKNKRTFLSPWISNIHEKK
GLTKYKSSPEKWSTASDPYSDFEKVTGRIDKNVSPEARHPLVAAYPIVHV
DMENIILSKNEDQSTQNTDSQTRTISKNTSTSRTHTAGFSNSNSSTVAID
HCLSLAGERTWAETMGLNTADTARLNANIRYVNTGTAPIYNVLPTTSLVL
GKNQTLATIKAKENQLSQILAPNNYYPSKNLAPIALNAQDDFSSTPITMN
YNQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQ
ETTARIIFNGKDLNLVERRIAAVNPSDPLETTKPDMTLKEALKIAFGFNE
PNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNATNIYTVLDKIKLNA
KMNILIRDKRFHYDRNNIAVGADESVVKEAHREVINSSTEGLLLNIDKDI
RKILSGYIVEIEDTEGLKEVINDRYDMLCISSLRQDGKTFIDFKKYNDKL
PLYISNPNYKVNVYAVTKENTIINPSENGDTSTNGIKKILIFSKKGYEIG
3D structure
PDB3tez Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
ChainA
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D177 D179 D181 I183 E188 D163 D165 D167 I169 E174
BS02 CA A D179 D181 E188 S222 K225 D235 D165 D167 E174 S208 K211 D221
BS03 MXE A T380 S382 D451 T345 S347 D416
BS04 MXE A S294 T295 S296 T331 S280 T281 S282 T296
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0090729 toxin activity
Biological Process
GO:0043409 negative regulation of MAPK cascade
GO:0044533 positive regulation of apoptotic process in another organism
GO:0051260 protein homooligomerization
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0020002 host cell plasma membrane
GO:0044164 host cell cytosol
GO:0044174 host cell endosome
GO:0044175 host cell endosome membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tez, PDBe:3tez, PDBj:3tez
PDBsum3tez
PubMed22063095
UniProtP13423|PAG_BACAN Protective antigen (Gene Name=pagA)

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