Structure of PDB 3tc3 Chain A

Receptor sequence
>3tc3A (length=289) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence]
HMRVGYVSTNYSLGCKADKTIKLSSLSEERVLKVSSSNLLCLKNILEWNL
KHEILFFRISSNTIPLASHPKFHVNWKDKLSHILGDIGDFIKENSIRISM
HPGQYVVLNSVREEVVRSSIMELKYHADLLDSMGIEGKIQIHVGSSMNGK
EESLNRFIENFRKLPSNISKRLVIENDDKVFSVKDCLWISERTGIPVIFD
NLHHSILNNGESLNDALSLVRRTWKDRPMIDYSEQEPGEKPGVHATTINE
ENFRRFVNEVDEVDIMLEVKDKEISALKAVKVLKELNKL
3D structure
PDB3tc3 UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A E174 D199 D230 E267 E175 D200 D231 E268
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0009411 response to UV

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Molecular Function

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Biological Process
External links
PDB RCSB:3tc3, PDBe:3tc3, PDBj:3tc3
PDBsum3tc3
PubMed23221644
UniProtQ4J9T1

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