Structure of PDB 3tbh Chain A

Receptor sequence
>3tbhA (length=318) Species: 5661 (Leishmania donovani) [Search protein sequence]
AAPFDKSKNVAQSIDQLIGQTPALYLNKLNNTKAKVVLKMECENPMASVK
DRLGFAIYDKAEKEGKLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIIT
MPESMSLERRCLLRIFGAEVILTPAALGMKGAVAMAKKIVAANPNAVLAD
QFATKYNALIHEETTGPEIWEQTNHNVDCFIAGVGTGGTLTGVARALKKM
GSHARIVAVEPTESPVLSGGKPGPHKIQGIGPGFVPDVLDRSLIDEVLCV
AGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEMEGKTIVTVIP
SFGERYLSTTLYRSVRDE
3D structure
PDB3tbh Crystal structure of O-Acetyl Serine Sulfhydrylase in complex with octapeptide derived from Serine Acetyl Transferase of Leishmania donovani
ChainA
Resolution1.68 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K51 S274
Catalytic site (residue number reindexed from 1) K50 S273
Enzyme Commision number 2.5.1.47: cysteine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S79 S80 T83 M130 Q152 P225 H226 G230 P233 S78 S79 T82 M129 Q151 P224 H225 G229 P232
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3tbh, PDBe:3tbh, PDBj:3tbh
PDBsum3tbh
PubMed
UniProtG1C2I2

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