Structure of PDB 3t92 Chain A

Receptor sequence
>3t92A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
DSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGG
CPICKQLIALAAYHAKHCQENKCPVPFCLNIKQKLRQQQLEASIDLSAYI
ESGEEQLLSDLFA
3D structure
PDB3t92 Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300.
ChainA
Resolution1.5 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H22 C26 C31 C36 H16 C20 C25 C30
BS02 ZN A H45 C49 C57 C60 H39 C43 C51 C54
BS03 ZN A H70 C74 C79 C84 H64 C68 C73 C78
BS04 TCE A Q94 E97 Q88 E91
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3t92, PDBe:3t92, PDBj:3t92
PDBsum3t92
PubMed25004968
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300);
Q15744

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