Structure of PDB 3t6q Chain A

Receptor sequence
>3t6qA (length=601) Species: 10090 (Mus musculus) [Search protein sequence]
QKCIEKEVNKTYNCENLGLNEIPGTLPNSTECLEFSFNVLPTIQNTTFSR
LINLTFLDLTRCQIYWIHEDTFQSQHRLDTLVLTANPLIFMAETALSGPK
ALKHLFFIQTGISSIDFIPLHNQKTLESLYLGSNHISSIKLPKGFPTEKL
KVLDFQNNAIHYLSKEDMSSLQQATNLSLNLNGNDIAGIEPGAFDSAVFQ
SLNFGGTQNLLVIFKGLKNSTIQSLWLGTFEDMDDEDISPAVFEGLCEMS
VESINLQKHYFFNISSNTFHCFSGLQELDLTATHLSELPSGLVGLSTLKK
LVLSANKFENLCQISASNFPSLTHLSIKGNTKRLELGTGCLENLENLREL
DLSHDDIETSDCCNLQLRNLSHLQSLNLSYNEPLSLKTEAFKECPQLELL
DLAFTRLKVKDAQSPFQNLHLLKVLNLSHSLLDISSEQLFDGLPALQHLN
LQGNHFPKGNIQKTNSLQTLGRLEILVLSFCDLSSIDQHAFTSLKMMNHV
DLSHNRLTSSSIEALSHLKGIYLNLASNHISIILPSLLPILSQQRTINLR
QNPLDCTCSNIYFLEWYKENMQKLEDTEDTLCENPPLLRGVRLSDVTLSC
S
3D structure
PDB3t6q Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A H379 Y405 H354 Y380
BS02 CU A E269 H295 E244 H270
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0002322 B cell proliferation involved in immune response
GO:0006954 inflammatory response
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045087 innate immune response
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005886 plasma membrane
GO:0072686 mitotic spindle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3t6q, PDBe:3t6q, PDBj:3t6q
PDBsum3t6q
PubMed21959264
UniProtQ62192|CD180_MOUSE CD180 antigen (Gene Name=Cd180)

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