Structure of PDB 3t1l Chain A

Receptor sequence
>3t1lA (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
PLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB3t1l Taloside inhibitors of galectin-1 and galectin-3
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MQT A R144 H158 R162 N174 W181 E184 R32 H46 R50 N62 W69 E72 MOAD: Kd=0.55mM
PDBbind-CN: -logKd/Ki=3.26,Kd=0.55mM
BindingDB: Kd=550000nM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:3t1l, PDBe:3t1l, PDBj:3t1l
PDBsum3t1l
PubMed22136701
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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