Structure of PDB 3syn Chain A

Receptor sequence

>3synA (length=258) Species: 1423 (Bacillus subtilis)

PEPLRKAEKLLQETGIKESTKTNTLKKLLRFSVEAGGLTEENVVGKLQEI
LCDMLPSADKWQEPIHSKYIVLFGSTGAGKTTTLAKLAAISMLEKHKKIA
FITTDTYRIAAVEQLKTYAELLQAPLEVCYTKEEFQQAKELFSEYDHVFV
DTAGRNFKDPQYIDELKETIPFESSIQSFLVLSATAKYEDMKHIVKRFSS
VPVNQYIFTKIDETTSLGSVFNILAESKIGVGFMTNGQNVPEDIQTVSPL
GFVRMLCR

3D structure

• PDB: 3syn Structural basis for the molecular evolution of SRP-GTPase activation by protein.
• Chain: A
• Resolution: 3.063 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	L201 Y226 L229 L230 Q346 V348 E350	L93 Y118 L121 L122 Q238 V240 E242
BS02	peptide	A	T214 Y215 R216 I217 R263	T106 Y107 R108 I109 R155
BS03	GDP	A	G185 G187 K188 T189 T190 K318 D320 E321 T343 G345 Q346	G77 G79 K80 T81 T82 K210 D212 E213 T235 G237 Q238
BS04	AF3	A	G185 K188 D213 R216 G262	G77 K80 D105 R108 G154

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005525 GTP binding

Biological Process

• GO:0006614 SRP-dependent cotranslational protein targeting to membrane

External links

• PDB: RCSB:3syn, PDBe:3syn, PDBj:3syn
• PDBsum: 3syn
• PubMed: 22056770
• UniProt: Q01960|FLHF_BACSU Flagellar biosynthesis protein FlhF (Gene Name=flhF)