Structure of PDB 3swg Chain A

Receptor sequence
>3swgA (length=417) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
YRDYFVIRGGKPLTGKVKISGAKNAALPIMFATILTEEPCTITNVPDLLD
VRNTLLLLRELGAELEFLNNTVFINPSINSFITNQEIIRRMRASVLSLGP
LLGRFGRAVVGLPGGCSIGARPIDQHLKFFKEAGADVEVREGYVYVNLKE
KRRVHFKFDLVTVTGTENALLYLASVPEESILENIALEPEVMDLIEVLKK
MGAHVKVEGRSAYVKGSENLKGFTHSVIPDRIEAGTFMVGAVLTDGEILL
ENARINHLRAVVEKLKLIGGEVVEENGNLRVFRKESLRACDIETQVYPGF
PTDMQAQFMALLSVAKGKSRIKENIFEHRFHHAQELNRLGANITVRGNTA
YVEGVERLYGSEVYSTDLRASASLVLAGLVAQGETVVRDVYHLDRGYEKL
EEKLKKLGADIERVSEL
3D structure
PDB3swg Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA).
ChainA
Resolution1.81 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K31 N32 C124 R129 D311 R403
Catalytic site (residue number reindexed from 1) K23 N24 C116 R121 D303 R395
Enzyme Commision number 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EPZ A K31 N32 R129 P130 I131 D132 Q133 L168 T170 V171 T172 D311 I333 F334 L376 K23 N24 R121 P122 I123 D124 Q125 L160 T162 V163 T164 D303 I325 F326 L368
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3swg, PDBe:3swg, PDBj:3swg
PDBsum3swg
PubMed22378791
UniProtO67315|MURA_AQUAE UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Gene Name=murA)

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