Structure of PDB 3swe Chain A

Receptor sequence
>3sweA (length=420) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence]
MDKFRVYGQSRLSGSVNISGAKNAALPILFAAILATEPVKLTNVPELKDI
ETTLKILRQLGVVVDRDATGAVLLDASNINHFTAPYELVKTMRASIWALA
PLVARFHQGQVSLPGGCSIGARPVDLHISGLEKLGADIVLEEGYVKAQVS
DRLVGTRIVIEKVSVGATLSIMMAATLAKGTTVIENAAREPEIVDTADFL
NKMGAKITGAGSAHITIEGVERLTGCEHSVVPDRIETGTFLIAAAISGGC
VVCQNTKADTLDAVIDKLREAGAQVDVTENSITLDMLGNRPKAVNIRTAP
HPGFPTDMQAQFTLLNMVAEGTSIITETIFENRFMHIPELIRMGGKAEIE
GNTAVCHGVEQLSGTEVIATDLRASISLVLAGCIATGETIVDRIYHIDRG
YEHIEDKLRGLGAKIERFSG
3D structure
PDB3swe Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA).
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K22 N23 D49 A94 C117 R122 D307 R399
Catalytic site (residue number reindexed from 1) K22 N23 D49 A94 C117 R122 D307 R399
Enzyme Commision number 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EPZ A K22 N23 W97 R122 P123 V124 D125 L126 S164 V165 G166 T306 D307 I329 F330 L372 K22 N23 W97 R122 P123 V124 D125 L126 S164 V165 G166 T306 D307 I329 F330 L372
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3swe, PDBe:3swe, PDBj:3swe
PDBsum3swe
PubMed22378791
UniProtP45025|MURA_HAEIN UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Gene Name=murA)

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