Structure of PDB 3sjz Chain A

Receptor sequence
>3sjzA (length=409) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]
AWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEETIKLGYAETNI
GVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLS
GAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSK
EEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPY
RDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVL
PGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLT
KADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKET
LMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWR
MIGWGLVEI
3D structure
PDB3sjz HOLD FOR PUBLICATION
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D19 K22 T23 T46 H97
Catalytic site (residue number reindexed from 1) D18 K21 T22 T40 H91
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A D19 G21 K22 T23 T24 N149 K150 D152 S184 L186 D18 G20 K21 T22 T23 N143 K144 D146 S178 L180
BS02 GNP A E39 E40 T46 D222 V223 K225 K234 S278 R280 A296 E38 E39 T40 D216 V217 K219 K228 S272 R274 A290
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003743 translation initiation factor activity
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation

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Molecular Function
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Biological Process
External links
PDB RCSB:3sjz, PDBe:3sjz, PDBj:3sjz
PDBsum3sjz
PubMed
UniProtQ980A5|IF2G_SACS2 Translation initiation factor 2 subunit gamma (Gene Name=eif2g)

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