Structure of PDB 3si5 Chain A

Receptor sequence
>3si5A (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
TGSQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLE
RAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQ
FYISWAEEYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQ
TL
3D structure
PDB3si5 Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E103 V106 E107 L131 C132 N133 D137 M138 Y141 E50 V53 E54 L78 C79 N80 D84 M85 Y88
Gene Ontology
Biological Process
GO:0007094 mitotic spindle assembly checkpoint signaling

View graph for
Biological Process
External links
PDB RCSB:3si5, PDBe:3si5, PDBj:3si5
PDBsum3si5
PubMed22000412
UniProtO60566|BUB1B_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (Gene Name=BUB1B)

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