Structure of PDB 3shr Chain A

Receptor sequence
>3shrA (length=278) Species: 9913 (Bos taurus) [Search protein sequence]
QAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDS
CIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRT
ATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE
ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPNEDP
VFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGL
DDVSNKAYEDAEAKAKYEAEAAFFANLK
3D structure
PDB3shr Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A K151 L156 F165 G166 E167 L168 A169 R176 T177 K74 L79 F88 G89 E90 L91 A92 R99 T100
Gene Ontology
Molecular Function
GO:0004692 cGMP-dependent protein kinase activity
GO:0005524 ATP binding
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3shr, PDBe:3shr, PDBj:3shr
PDBsum3shr
PubMed21893290
UniProtP00516|KGP1_BOVIN cGMP-dependent protein kinase 1 (Gene Name=PRKG1)

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