Structure of PDB 3shb Chain A

Receptor sequence
>3shbA (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
SGPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDP
PLSSVPSEDEWYCPECR
3D structure
PDB3shb Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A C329 P340 D341 Q343 L344 M345 C346 D347 D350 E368 D369 C19 P30 D31 Q33 L34 M35 C36 D37 D40 E58 D59
BS02 ZN A C315 C318 C326 C329 C5 C8 C16 C19
BS03 ZN A C331 C334 H354 C357 C21 C24 H44 C47
BS04 ZN A C346 C349 C373 C376 C36 C39 C63 C66
BS05 ZN A H332 E375 H22 E65
External links
PDB RCSB:3shb, PDBe:3shb, PDBj:3shb
PDBsum3shb
PubMed21808300
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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