Structure of PDB 3s9f Chain A

Receptor sequence
>3s9fA (length=144) Species: 5664 (Leishmania major) [Search protein sequence]
SGVAKHLGEALKLRKQADTADMDSLSGKTVFFYFSASWCPPCRGFTPQLV
EFYEKHHDSKNFEIILASWDEEEDDFNAYYAKMPWLSIPFANRNIVEALT
KKYSVESIPTLIGLNADTGDTVTTRARHALTQDPMGEQFPWRDE
3D structure
PDB3s9f The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T111 L112 T125 R126 R128 T110 L111 T124 R125 R127
BS02 MG A P90 F91 P89 F90
BS03 MG A H7 E10 A11 H6 E9 A10
Gene Ontology
Molecular Function
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
GO:0046872 metal ion binding
Biological Process
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3s9f, PDBe:3s9f, PDBj:3s9f
PDBsum3s9f
PubMed22928053
UniProtE9ADX4

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