Structure of PDB 3s9e Chain A

Receptor sequence
>3s9eA (length=253) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFS
YEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAID
FSKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSK
ISTFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRN
CNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWW
RCP
3D structure
PDB3s9e Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A Y63 L91 T92 R97 G142 A143 T144 E191 Y61 L89 T90 R95 G140 A141 T142 E189 PDBbind-CN: -logKd/Ki=5.13,Ki=7.43uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3s9e, PDBe:3s9e, PDBj:3s9e
PDBsum3s9e
PubMed21907808
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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