Structure of PDB 3s91 Chain A

Receptor sequence
>3s91A (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
TNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGT
IKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ
KVAQMPQ
3D structure
PDB3s91 Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1
ChainA
Resolution2.06 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JQ1 A W57 P58 V63 L68 L70 N116 I122 W22 P23 V28 L33 L35 N81 I87
External links
PDB RCSB:3s91, PDBe:3s91, PDBj:3s91
PDBsum3s91
PubMed
UniProtQ15059|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)

[Back to BioLiP]