Structure of PDB 3s6b Chain A

Receptor sequence
>3s6bA (length=345) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
HLKTIVKKHLSPENFDPTNRKYWVYDDHLKNFVNFKFTGDVRPWPLSKIN
HVPSHIERPDYAISSIPESELIYKRKSDIYVNNEEEIQRIREACILGRKT
LDYAHTLVSPGVTTDEIDRKVHEFIIKNNAYPSTLNYYKFPKSCCTSVNE
IVCHGIPDYRPLKSGDIINIDISVFYKGVHSDLNETYFVGDINDVPKEGK
ELVETCYFSLMEAIKKCKPGMFYKNIGTLIDAYVSKKNFSVVRSYSGHGV
GKLFHSNPTVPHFKKNKAVGIMKPGHVFTIEPMINQGHYSDVLWPDQWTS
ATSDGKLSAQFEHTLLITNNGVEILTKRTQDSPPLGFDTKDELYY
3D structure
PDB3s6b Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D193 D204 H270 H277 E303 E334
Catalytic site (residue number reindexed from 1) D171 D182 H248 H255 E281 E312
Enzyme Commision number 3.4.11.18: methionyl aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D204 H270 E303 E334 D182 H248 E281 E312
Gene Ontology
Molecular Function
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3s6b, PDBe:3s6b, PDBj:3s6b
PDBsum3s6b
PubMed
UniProtQ8IJP2|MAP1B_PLAF7 Methionine aminopeptidase 1b (Gene Name=METAP1b)

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