Structure of PDB 3rzm Chain A

Receptor sequence
>3rzmA (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]
HSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRR
VAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTA
3D structure
PDB3rzm Duplex interrogation by a direct DNA repair protein in search of base damage
ChainA
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A V101 F102 H106 P109 R110 F124 S125 H167 I168 C169 E170 H171 Y235 R254 V47 F48 H52 P55 R56 F70 S71 H113 I114 C115 E116 H117 Y175 R194
BS02 dna A F102 G103 R176 R198 R241 K242 K243 F48 G49 R122 R144 R181 K182 K183
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:3rzm, PDBe:3rzm, PDBj:3rzm
PDBsum3rzm
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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