Structure of PDB 3rzh Chain A

Receptor sequence
>3rzhA (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
HSWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGK
WHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFN
FVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRP
SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKIL
L
3D structure
PDB3rzh Duplex interrogation by a direct DNA repair protein in search of base damage
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A V101 F102 H106 R110 F124 S125 H167 I168 C169 H171 D173 E175 Y235 V47 F48 H52 R56 F70 S71 H113 I114 C115 H117 D119 E121 Y178
BS02 dna A F102 G103 R198 R241 K243 F48 G49 R144 R184 K186
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:3rzh, PDBe:3rzh, PDBj:3rzh
PDBsum3rzh
PubMed22659876
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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