Structure of PDB 3rw6 Chain A

Receptor sequence
>3rw6A (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
NWFKITIPYGRKYDKAWLLSMIQSKCSVPFTPIEFHYENTRAQFFVEDAS
TASALKAVNYKILDRENRRISIIINSSAPPHTILNELKPEQVEQLKLIMS
KRYDGSQQALDLKGLRSDPDLVAQNIDVVLNRRSCMAATLRIIEENIPEL
LSLNLSNNRLYRLDDMSSIVQKAPNLKILNLSGNELKSERELDKIKGLKL
EELWLDGNSLCDTFRDQSTYISAIRERFPKLLRLDGHELPPPIAF
3D structure
PDB3rw6 Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A T123 Y126 E151 H153 Y154 R158 I190 N192 R233 V246 N248 N275 R276 Y278 K304 S305 T6 Y9 E34 H36 Y37 R41 I73 N75 R116 V129 N131 N158 R159 Y161 K187 S188 PDBbind-CN: Kd=0.09uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006406 mRNA export from nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3rw6, PDBe:3rw6, PDBj:3rw6
PDBsum3rw6
PubMed21822283
UniProtQ9UBU9|NXF1_HUMAN Nuclear RNA export factor 1 (Gene Name=NXF1)

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