Structure of PDB 3rsm Chain A

Receptor sequence
>3rsmA (length=436) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
SIFRALTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQG
LVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGCNGFKIVVAGETLA
NEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVV
DCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLI
AKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPG
ADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMS
GHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEIN
ITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTP
VLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF
3D structure
PDB3rsm Solution NMR of a 463-residue phosphohexomutase: domain 4 mobility, substates, and phosphoryl transfer defect.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C108 K118 D242 D244 D246 R247 H329 D340
Catalytic site (residue number reindexed from 1) C87 K91 D215 D217 D219 R220 H302 D313
Enzyme Commision number 5.4.2.2: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
5.4.2.8: phosphomannomutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D242 D244 D246 D215 D217 D219
BS02 PO4 A C108 D242 D244 D246 R247 C87 D215 D217 D219 R220
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004614 phosphoglucomutase activity
GO:0004615 phosphomannomutase activity
GO:0016853 isomerase activity
GO:0016868 intramolecular phosphotransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process
GO:0009244 lipopolysaccharide core region biosynthetic process
GO:0009298 GDP-mannose biosynthetic process
GO:0042121 alginic acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3rsm, PDBe:3rsm, PDBj:3rsm
PDBsum3rsm
PubMed22242625
UniProtP26276|ALGC_PSEAE Phosphomannomutase/phosphoglucomutase (Gene Name=algC)

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