Structure of PDB 3rsj Chain A

Receptor sequence
>3rsjA (length=406) Species: 1491 (Clostridium botulinum) [Search protein sequence]
IKDNSILDMRYENNKFIDISGYGSNISINGDVYIYSTNRNQFGIYSSKPS
EVNIAQNNDIIYNGRYQNFSISFWVRIPKYFNKVNLNNEYTIIDCIRNNN
SGWKISLNYNKIIWTLQDTAGNNQKLVFNYTQMISISDYINKWIFVTITN
NRLGNSRIYINGNLIDEKSISNLGDIHVSDNILFKIVGCNDTRYVGIRYF
KVFDTELGKTEIETLYSDEPDPSILKDFWGNYLLYNKRYYLLNLLRTDKS
ITQNSNFLNINQQRGVYQKPNIFSNTRLYTGVEVIIRKNGNTDNFVRKND
LAYINVVDRDVEYRLYADISIAKPEKIIKLIRTSNNSLGQIIVMDSIGNN
CTMNFQNNNGGNIGLLGFHSNNLVASSWYYNNIRKNTSSNGCFWSFISKE
HGWQEN
3D structure
PDB3rsj Unique ganglioside recognition strategies for clostridial neurotoxins.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q906 N973
Catalytic site (residue number reindexed from 1) Q41 N108
Enzyme Commision number 3.4.24.69: bontoxilysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A E1195 F1240 H1241 S1248 W1250 E325 F368 H369 S376 W378
BS02 SIA A L1110 R1256 L245 R384
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:3rsj, PDBe:3rsj, PDBj:3rsj
PDBsum3rsj
PubMed21849494
UniProtA7GBG3|BXF_CLOBL Botulinum neurotoxin type F (Gene Name=F)

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