Structure of PDB 3rs8 Chain A

Receptor sequence
>3rs8A (length=490) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
HMKEIDELTIKEYGVDSRILMERAGISVVLAMEEELGNLSDYRFLVLCGG
GNNGGDGFVVARNLLGVVKDVLVVFLGKKKTPDCEYNYGLYKKFGGKVVE
QFEPSILNEFDVVVDAIFGTGLRGEITGEYAEIINLVNKSGKVVVSVDVP
SGIDSNTGKVLRTAVKADLTVTFGVPKIGHILFPGRDLTGKLKVANIGHP
VHLINSINRYVITREMVRSLLPERPRDSHKGTYGKVLIIAGSRLYSGAPV
LSGMGSLKVGTGLVKLAVPFPQNLIATSRFPELISVPIDTEKGFFSLQNL
QECLELSKDVDVVAIGPGLGNNEHVREFVNEFLKTLEKPAVIDADAINVL
DTSVLKERKSPAVLTPHPGEMARLVKKTVGDVKYNYELAEEFAKENDCVL
VLKSATTIVTDGEKTLFNITGNTGLSKGGSGDVLTGMIAGFIAQGLSPLE
ASTVSVYLHGFAAELFEQDERGLTASELLRLIPEAIRRLK
3D structure
PDB3rs8 Identification of unknown protein function using metabolite cocktail screening.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.136: ADP-dependent NAD(P)H-hydrate dehydratase.
5.1.99.6: NAD(P)H-hydrate epimerase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity
GO:0052856 NAD(P)HX epimerase activity
Biological Process
GO:0046496 nicotinamide nucleotide metabolic process
GO:0110051 metabolite repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3rs8, PDBe:3rs8, PDBj:3rs8
PDBsum3rs8
PubMed22940582
UniProtQ9X024|NNR_THEMA Bifunctional NAD(P)H-hydrate repair enzyme Nnr (Gene Name=nnr)

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