Structure of PDB 3rph Chain A

Receptor sequence
>3rphA (length=277) Species: 1423 (Bacillus subtilis) [Search protein sequence]
AMNVPFWTEEHVRATLPERDAESHKGTYGTALLLAGSDDMPGAALLAGLG
AMRSGLGKLVIGTSENVIPLIVPVLPEATYWRDGWKKAADAQLEETYRAI
AIGPGLPQTESVQQAVDHVLTADCPVILDAGALAKRTYPKREGPVILTPH
PGEFFRMTGVPVNELQKKRAEYAKEWAAQLQTVIVLKGNQTVIAFPDGDC
WLNPTGNGALAKGGTGDTLTGMILGMLCCHEDPKHAVLNAVYLHGACAEL
WTDEHSAHTLLAHELSDILPRVWKRFE
3D structure
PDB3rph Identification of unknown protein function using metabolite cocktail screening.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.136: ADP-dependent NAD(P)H-hydrate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A K186 G187 N206 L209 A210 T214 G215 K187 G188 N207 L210 A211 T215 G216
BS02 AMP A H149 P150 H150 P151
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
GO:0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity
GO:0052856 NAD(P)HX epimerase activity
Biological Process
GO:0046496 nicotinamide nucleotide metabolic process
GO:0110051 metabolite repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3rph, PDBe:3rph, PDBj:3rph
PDBsum3rph
PubMed22940582
UniProtP94368|NNRD_BACSU ADP-dependent (S)-NAD(P)H-hydrate dehydratase (Gene Name=nnrD)

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