Structure of PDB 3rlg Chain A

Receptor sequence
>3rlgA (length=278) Species: 58218 (Loxosceles intermedia) [Search protein sequence]
GNRRPIWIMGAMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIP
CDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDN
QANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLT
KDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRG
LSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDV
ITDVLNEAAYKKKFRVATYDDNPWVTFK
3D structure
PDB3rlg Crystallization and preliminary X-ray diffraction analysis of a class II phospholipase D from Loxosceles intermedia venom.
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A12 E32 D34 H47 G48 D52 D91 K93 W230 D233 N252
Catalytic site (residue number reindexed from 1) A11 E31 D33 H47 G48 D52 D91 K93 W224 D227 N246
Enzyme Commision number 4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E32 D34 D91 E31 D33 D91
Gene Ontology
Molecular Function
GO:0008081 phosphoric diester hydrolase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0090729 toxin activity
Biological Process
GO:0006629 lipid metabolic process
GO:0016042 lipid catabolic process
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:3rlg, PDBe:3rlg, PDBj:3rlg
PDBsum3rlg
PubMed21301094
UniProtP0CE80|A1HA_LOXIN Dermonecrotic toxin LiSicTox-alphaIA1a

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