Structure of PDB 3rja Chain A

Receptor sequence

>3rjaA (length=473) Species: 5520 (Microdochium nivale)

GAIEACLSAAGVPIDIPGTADYERDVEPFNIRLPYIPTAIAQTQTTAHIQ
SAVQCAKKLNLKVSAKSGGHSYASFGFGGENGHLMVQLDRMIDVISYNDK
TGIAHVEPGARLGHLATVLNDKYGRAISHGTCPGVGISGHFAHGGFGFSS
HMHGLAVDSVVGVTVVLADGRIVEASATENADLFWGIKGAGSNFGIVAVW
KLATFPAPKVLTRFGVTLNWKNKTSALKGIEAVEDYARWVAPREVNFRIG
DYGAGNPGIEGLYYGTPEQWRAAFQPLLDTLPAGYVVNPTTSLNWIESVL
SYSNFDHVDFITPQPVENFYAKSLTLKSIKGDAVKNFVDYYFDVSNKVKD
RFWFYQLDVHGGKNSQVTKVTNAETAYPHRDKLWLIQFYDRYDNNQTYPE
TSFKFLDGWVNSVTKALPKSDWGMYINYADPRMDRDYATKVYYGENLARL
QKLKAKFDPTDRFYYPQAVRPVK

3D structure

• PDB: 3rja Crystallization of carbohydrate oxidase from Microdochium nivale.
• Chain: A
• Resolution: 2.1 Å

Enzymatic activity

• Enzyme Commision number: 1.1.3.-
  1.1.3.5: hexose oxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	F29 A65 K66 S67 G68 G69 H70 S71 G130 T131 C132 V135 G136 S138 G139 H140 F146 S192 I196 V197 Q314 Y425 N427 Y428	F29 A65 K66 S67 G68 G69 H70 S71 G130 T131 C132 V135 G136 S138 G139 H140 F146 S192 I196 V197 Q314 Y425 N427 Y428
BS02	ZN	A	H114 D309	H114 D309
BS03	ZN	A	D306 H307	D306 H307
BS04	ZN	A	E231 D235	E231 D235
BS05	ABL	A	Y72 C132 Y252 N304 Q356 Q387 Y389 R391 Y428	Y72 C132 Y252 N304 Q356 Q387 Y389 R391 Y428
BS06	ABL	A	I14 D15 I16 T19 D21 Q42	I14 D15 I16 T19 D21 Q42

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0046562 glucose oxidase activity
• GO:0046872 metal ion binding
• GO:0047979 hexose oxidase activity
• GO:0050660 flavin adenine dinucleotide binding
• GO:0071949 FAD binding

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3rja, PDBe:3rja, PDBj:3rja
• PDBsum: 3rja
• UniProt: I1SB12|MNCO_MICNN Carbohydrate oxidase (Gene Name=MnCO)