Structure of PDB 3rgg Chain A

Receptor sequence
>3rggA (length=156) Species: 158 (Treponema denticola) [Search protein sequence]
RPLVIILMGSSSDMGHAEKIASELKTFGIEYAIRIGSAHKTAEHVVSMLK
EYEALDRPKLYITIAGRSNALSGFVDGFVKGATIACPPPSDSFAGADIYS
SLRMPSGISPALVLEPKNAALLAARIFSLYDKEIADSVKSYMESNAQKII
EDDSKL
3D structure
PDB3rgg Treponema denticola PurE Is a Bacterial AIR Carboxylase.
ChainA
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.21: phosphoribosylaminoimidazole carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AIR A S11 D14 S38 H40 K41 A66 G67 R68 S69 S10 D13 S37 H39 K40 A65 G66 R67 S68
Gene Ontology
Molecular Function
GO:0004638 phosphoribosylaminoimidazole carboxylase activity
GO:0016829 lyase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3rgg, PDBe:3rgg, PDBj:3rgg
PDBsum3rgg
PubMed21548610
UniProtQ73PV9|PURE_TREDE Phosphoribosylaminoimidazole carboxylase (Gene Name=purE)

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