Structure of PDB 3rfm Chain A

Receptor sequence
>3rfmA (length=291) Species: 9606 (Homo sapiens) [Search protein sequence]
SVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADILVG
VLAIPFAITISTGFCAACHGCLFIACFVLVLAQSSIFSLLAIAIDRYIAI
AIPLRYNGLVTGTRAAGIIAICWVLSFAIGLTPMLGWNNCGQPGCGEGQV
ACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFAAARRQLKQMESQ
PLPGERARSTLQKEVHAAKSAAIIAGLFALCWLPLHIINCFTFFCPDCSH
APLWLMYLAIVLAHTNSVVNPFIYAYRIREFRQTFRKIIRS
3D structure
PDB3rfm Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
ChainA
Resolution3.598 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CFF A F168 I274 F154 I260 BindingDB: Ki=23400nM
Gene Ontology
Molecular Function
GO:0001609 G protein-coupled adenosine receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:3rfm, PDBe:3rfm, PDBj:3rfm
PDBsum3rfm
PubMed21885291
UniProtP29274|AA2AR_HUMAN Adenosine receptor A2a (Gene Name=ADORA2A)

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