Structure of PDB 3reg Chain A

Receptor sequence
>3regA (length=171) Species: 5759 (Entamoeba histolytica) [Search protein sequence]
KKALKIVVVGDGAVGKTCLLLAFSKGEIPTAYVPTVFENFSHVMKYKNEE
FILHLWDTAGQEEYDRLRPLSYADSDVVLLCFAVNNRTSFDNISTKWEPE
IKHYIDTAKTVLVGLKVDLRKDGSDDVTKQEGDDLCQKLGCVAYIEASSV
AKIGLNEVFEKSVDCIFSNKP
3D structure
PDB3reg Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica.
ChainA
Resolution1.801 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSP A A30 V31 G32 K33 T34 C35 Y49 P51 T52 G77 K133 D135 L136 S165 V167 A13 V14 G15 K16 T17 C18 Y32 P34 T35 G60 K116 D118 L119 S148 V150
BS02 MG A T34 T52 T17 T35
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:3reg, PDBe:3reg, PDBj:3reg
PDBsum3reg
PubMed21930699
UniProtP31021|RHO1_ENTH1 Ras-like GTP-binding protein RHO1 (Gene Name=RHO1)

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