Structure of PDB 3r9b Chain A

Receptor sequence
>3r9bA (length=391) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
AQGLLLQLLDPATRADPYPIYDRIRRGGPLALPEANLAVFSSFSDCDDVL
RHPSSCSDRTKSTIFQRQLAPASFLFLDPPDHTRLRGLVSKAFAPRVIKR
LEPEITALVDQLLDAVDGPEFNLIDNLAYPLPVAVICRLLGVPIEDEPKF
SRASALLAAALDPFLALTGETSDLFDEQMKAGMWLRDYLRALIDERRRTP
GEDLMSGLVAVEESGDQLTEDEIIATCNLLLIAGHETTVNLIANAALAML
RTPGQWAALAADGSRASAVIEETMRYDPPVQLVSRYAGDDLTIGTHTVPK
GDTMLLLLAAAHRDPTIVGAPDRFDPDRAQIRHLGFGKGAHFCLGAPLAR
LEATVALPALAARFPEARLSGEPEYKRNLTLRGMSTLSIAV
3D structure
PDB3r9b An enlarged, adaptable active site in CYP164 family P450 enzymes, the sole P450 in Mycobacterium leprae.
ChainA
Resolution1.89 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A182 A256 E259 T260 T261 F359 C366 L367 G368 E375 L404
Catalytic site (residue number reindexed from 1) A159 A233 E236 T237 T238 F336 C343 L344 G345 E352 L381
Enzyme Commision number 1.14.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A F97 L98 H105 R109 L253 A256 T260 L264 V306 R308 G358 F359 H364 C366 G368 A372 F74 L75 H82 R86 L230 A233 T237 L241 V283 R285 G335 F336 H341 C343 G345 A349
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3r9b, PDBe:3r9b, PDBj:3r9b
PDBsum3r9b
PubMed22037849
UniProtA0R5U2

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