Structure of PDB 3r8x Chain A

Receptor sequence
>3r8xA (length=309) Species: 632 (Yersinia pestis) [Search protein sequence]
AMSDSLRIIFAGTPDFAARHLGALLSSQHKIVGVFTQPDRPLTPSPVKIL
AEHHGIPVFQPKSLRPEENQHLVADLNADIMVVVAYGLILPAAVLAMPRL
GCINVHGSLLPRWRGAAPIQRSVWAGDEKTGITIMQMDIGLDTGAMLHKI
ECAIQPEDTSATLYDKLAQLGPQGLLITLQQLAAGTALAEVQNETQATYA
EKLSKEEAKLDWTLSATQLERCIRAFNPWPVSYFIVDEQPIKVWQAQVLP
AGEDAEPGTIIHADKHGIQVATADGVLNITQLQPAGKKAMSAADLLNSRR
EWFIPGSQL
3D structure
PDB3r8x Crystal Structure of Methionyl-tRNA Formyltransferase from Yersinia pestis complexed with L-methionine
ChainA
Resolution2.256 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H111 D147
Catalytic site (residue number reindexed from 1) H106 D142
Enzyme Commision number 2.1.2.9: methionyl-tRNA formyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MET A A90 Y91 N109 H111 D147 A85 Y86 N104 H106 D142
BS02 MOE A E162 T164 R229 W249 Q250 E157 T159 R224 W244 Q245
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004479 methionyl-tRNA formyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
GO:0009058 biosynthetic process
GO:0019988 charged-tRNA amino acid modification
GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:3r8x, PDBe:3r8x, PDBj:3r8x
PDBsum3r8x
PubMed
UniProtQ8ZJ80|FMT_YERPE Methionyl-tRNA formyltransferase (Gene Name=fmt)

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