Structure of PDB 3r8f Chain A

Receptor sequence
>3r8fA (length=319) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
DFLNPKYTLENFIVGEGNRLAYEVVKEALENLGSLYNPIFIYGSVGTGKT
HLLQAAGNEAKKRGYRVIYSSADDFAQAMVEHLKKGTINEFRNMYKSVDL
LLLDDVQFLSGKERTQIEFFHIFNTLYLLEKQIILASDRHPQKLDGVSDR
LVSRFEGGILVEIELDNKTRFKIIKEKLKEFNLELRKEVIDYLLENTKNV
REIEGKIKLIKLKGFEGLERKERKERDKLMQIVEFVANYYAVKVEDILSD
KNKRTSEARKIAMYLCRKVCSASLIEIARAFKRKDHTTVIHAIRSVEEEK
RKFKHLVGFLEKQAFDKIC
3D structure
PDB3r8f DNA stretching by bacterial initiators promotes replication origin opening.
ChainA
Resolution3.366 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K188 E189 R190 T191 K112 E113 R114 T115 PDBbind-CN: Kd=0.11uM
BS02 MG A T126 D180 D181 T50 D104 D105
BS03 ACP A Y83 N87 F88 I89 G122 G124 K125 T126 H127 K253 V276 R277 E280 Y7 N11 F12 I13 G46 G48 K49 T50 H51 K177 V200 R201 E204
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006270 DNA replication initiation
GO:0006275 regulation of DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3r8f, PDBe:3r8f, PDBj:3r8f
PDBsum3r8f
PubMed21964332
UniProtO66659|DNAA_AQUAE Chromosomal replication initiator protein DnaA (Gene Name=dnaA)

[Back to BioLiP]