Structure of PDB 3r7g Chain A

Receptor sequence
>3r7gA (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
RDALSLEEILRLYNQPINEEQAWAVCYQCCGSLRAAARRRQPRHRVRSAA
QIRVWRDGAVTLAPAADQCMETEVIESLGIIIYKALDYGLKENEERELSP
PLEQLIDHMANTVEAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAE
TMEL
3D structure
PDB3r7g Structure of the Spire KIND domain and insights into its interaction with Fmn-family formins
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A P52 E127 Y134 D138 E143 N144 E145 E146 R147 E148 I157 D158 A161 T163 P16 E76 Y83 D87 E92 N93 E94 E95 R96 E97 I106 D107 A110 T112
Gene Ontology
Biological Process
GO:0016192 vesicle-mediated transport
GO:0045010 actin nucleation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3r7g, PDBe:3r7g, PDBj:3r7g
PDBsum3r7g
PubMed
UniProtQ08AE8|SPIR1_HUMAN Protein spire homolog 1 (Gene Name=SPIRE1)

[Back to BioLiP]