Structure of PDB 3r5z Chain A

Receptor sequence
>3r5zA (length=140) Species: 37329 (Nocardia farcinica) [Search protein sequence]
GEYEPSPSDWARKQVETYENSGGTEGTTLQGKPVVVLTTKGAKTGKLRKT
PLMRVEHNGEYAVVASLGGAPKHPVWYHNIKAEPHVELRDGTEVGDYTAR
EVTGEEKRVWWERAVEVWPDYAEYQTKTTREIPVFVLTPR
3D structure
PDB3r5z Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
ChainA
Resolution1.503 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 F42 A W14 A15 Q18 L33 G45 A46 K47 T48 R52 T54 P55 L56 M57 V68 L71 P78 V79 W80 N83 Y125 W10 A11 Q14 L29 G41 A42 K43 T44 R48 T50 P51 L52 M53 V64 L67 P74 V75 W76 N79 Y121
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0070967 coenzyme F420 binding
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:3r5z, PDBe:3r5z, PDBj:3r5z
PDBsum3r5z
PubMed22244759
UniProtQ5YYT7

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