Structure of PDB 3r3w Chain A

Receptor sequence
>3r3wA (length=295) Species: 1076 (Rhodopseudomonas palustris) [Search protein sequence]
LADLFPGFGSEWINTSSGRIFARVGGDGPPLLLLHGFPQTHVMWHRVAPK
LAERFKVIVADLPGYGWSDMPESDEQHTPYTKRAMAKQLIEAMEQLGHVH
FALAGHNRGARVSYRLALDSPGRLSKLAVLDILPTYEYWQRMNRAYALKI
YHWSFLAQPAPLPENLLGGDPDFYVKAKLASWTRAGDLSAFDPRAVEHYR
IAFADPMRRHVMCEDYRAGAYADFEHDKIDVEAGNKIPVPMLALWGASGI
AAATPLDVWRKWASDVQGAPIESGHFLPEEAPDQTAEALVRFFSA
3D structure
PDB3r3w Mapping the reaction coordinates of enzymatic defluorination.
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F40 Q42 H109 N110 R111 D134 H155 Y219 H280
Catalytic site (residue number reindexed from 1) F37 Q39 H106 N107 R108 D131 H152 Y216 H275
Enzyme Commision number 3.8.1.3: haloacetate dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R3W A N110 R111 R114 H155 W185 Y219 N107 R108 R111 H152 W182 Y216
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018785 haloacetate dehalogenase activity

View graph for
Molecular Function
External links
PDB RCSB:3r3w, PDBe:3r3w, PDBj:3r3w
PDBsum3r3w
PubMed21510690
UniProtQ6NAM1|DEHA_RHOPA Fluoroacetate dehalogenase (Gene Name=RPA1163)

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