Structure of PDB 3r3l Chain A

Receptor sequence
>3r3lA (length=513) [Search protein sequence]
KSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKQ
RRDDSDLKRLRDLNQAVNNLVELKSTQQKSVLRVGTLSSDDLLTLAADLE
KLKSKVTRTERPLSSGVYMGNLSSQQLDQRRALLNLIGMDGVVRVWDVKN
AELLNNQFGTMPSLTLACLTKQGQVDLNDVVQALTDLGLIYTAKYPNTSD
LDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETI
KVSPQSMDGILKSILKVKRALGMFVSDTPGERNPYENILYKICLSGDGWP
YIASRTSIVGRAWENTVVDLGLTYSQLMTLKDAMLQLDPNAKTWMDIEGR
PEDPVEVALYQPISGCYIHFFREPTDLKQFKQDAKYSHGIDIADLFAAQP
GLTSAVIEALPRNMVITCQGSEDIKKLLESQGRKDIKLIDIALSKIDSRK
FENAVWDQYKDLCHMHTGVVVEKKEEITPHCALMDCIMFDAAVSGGLNTL
VLRAVLPRDMVFR
3D structure
PDB3r3l Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy.
ChainA
Resolution2.449 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D204 H226 D186 H208
BS02 MN A D389 E391 D533 D346 E348 D485
BS03 ZN A E399 C506 H509 C529 E356 C463 H466 C481
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0019049 virus-mediated perturbation of host defense response
GO:0039689 negative stranded viral RNA replication
GO:0039696 RNA-templated viral transcription
GO:0039724 symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3r3l, PDBe:3r3l, PDBj:3r3l
PDBsum3r3l
PubMed21917929
UniProtQ9DQX7

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