Structure of PDB 3r1j Chain A

Receptor sequence
>3r1jA (length=246) Species: 243243 (Mycobacterium avium 104) [Search protein sequence]
ITVTKLGSRIGARVDGVRLGGDLDDATVEQIRRALLTHKVIFFRHQHHLD
DSRQLEFARLLGTPIGATRWHTDVTFAANYPAASILRAVTLPSYGGSTLW
ASTVAAYQQLPEPLRHLTENLWALHTNRPDFRTEHPVVRVHPETGERALL
AGDFVRGFVGLDGHESSVLLELLQRRITMPENTVRWSWAPGDVAMWDNRA
TQHRAIDDYDDQPRLMHRITLMGDVPVNVHGERSRVISGAPLEVLA
3D structure
PDB3r1j Increasing the structural coverage of tuberculosis drug targets.
ChainA
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H99 D101 H253 R268
Catalytic site (residue number reindexed from 1) H71 D73 H203 R218
Enzyme Commision number 1.14.11.17: taurine dioxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H99 D101 H253 H71 D73 H203
Gene Ontology
Molecular Function
GO:0000908 taurine dioxygenase activity
GO:0016491 oxidoreductase activity
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:3r1j, PDBe:3r1j, PDBj:3r1j
PDBsum3r1j
PubMed25613812
UniProtA0A0H2ZSG9

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