Structure of PDB 3qyq Chain A

Receptor sequence
>3qyqA (length=273) Species: 508771 (Toxoplasma gondii ME49) [Search protein sequence]
NLYFQGIYKQFTSRTLLNFFEVAALTDGETNESVAAVCKIAAKDPAIVGV
SVRPAFVRFIRQELVKSAPEVAGIKVCAAVNFPEGTGTPDTVSLEAVGAL
KDGADEIECLIDWRRMNENVADGESRIRLLVSEVKKVVGPKTLKVVLSGG
ELQGGDIISRAAVAALEGGADFLQTSSGLGATHATMFTVHLISIALREYM
VRENERIRVEGVRCIGIKIEVGDVHMAETADFLMQMIFENGPRSIVRDKF
RVGGGFNLLKELRDCYESWDSVG
3D structure
PDB3qyq Structural and functional divergence of the aldolase fold in Toxoplasma gondii.
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E107 Q173 K224
Catalytic site (residue number reindexed from 1) E108 Q174 K218
Enzyme Commision number 4.1.2.4: deoxyribose-phosphate aldolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A G27 S32 G28 S33
BS02 FRU A E28 S32 V36 F262 E29 S33 V37 F256
BS03 GLC A E83 E150 E84 E151
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004139 deoxyribose-phosphate aldolase activity
GO:0016829 lyase activity
Biological Process
GO:0009264 deoxyribonucleotide catabolic process
GO:0016052 carbohydrate catabolic process
GO:0046386 deoxyribose phosphate catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3qyq, PDBe:3qyq, PDBj:3qyq
PDBsum3qyq
PubMed25284756
UniProtA0A7J6KBZ0|DPA_TOXGO Divergent deoxyribose-phosphate aldolase-like protein (Gene Name=DPA)

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