Structure of PDB 3qy8 Chain A

Receptor sequence
>3qy8A (length=243) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRRKGMFET
PEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLN
DSRYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRV
RELIDMGCYTQVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDM
HNLDGRPPHMAEAYDLVTQKYGEAKAQELFIDNPRKIVMDQLI
3D structure
PDB3qy8 Crystal structures of YwqE from Bacillus subtilis and CpsB from Streptococcus pneumoniae, unique metal-dependent tyrosine phosphatases.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A E80 E108 H136 R139 E80 E108 H136 R139
BS02 FE A H5 H7 E80 D199 H5 H7 E80 D199
BS03 MG A D14 H42 H201 D14 H42 H201
BS04 SO4 A H7 H42 R139 D199 H201 H7 H42 R139 D199 H201
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0030145 manganese ion binding
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0045227 capsule polysaccharide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3qy8, PDBe:3qy8, PDBj:3qy8
PDBsum3qy8
PubMed21605684
UniProtQ9AHD4|CPSB_STRPN Tyrosine-protein phosphatase CpsB (Gene Name=cpsB)

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